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Guz komórek tucznych u kotów – opis przypadku - Vetkompleksowo – serwis dla lekarzy weterynarii
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Wyszukaj w serwisie


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Guz komórek tucznych u kotów – opis przypadku


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Guz komórek tucznych (MCT – ang. mast cell tumor) jest jednym z najczęściej występujących nowotworów skóry u psów (18) i drugim co do częstości występowania u kotów. Wyróżnia się dwie formy mastocytomy – skórną, która diagnozowana jest najczęściej oraz trzewną – obejmującą narządy wewnętrzne.

Guz komórek tucznych jest nowotworem wywodzącym się ze stransformowanych nowotworowo mastocytów, który może obejmować wiele narządów i wykazywać różne zachowanie biologiczne. Obraz kliniczny jest różnorodny i w dużej mierze zależy od lokalizacji zmiany oraz stopnia histologicznej złośliwości nowotworu. Przebieg kliniczny oraz klasyfikacja histologiczna guzów komórek tucznych u psów i kotów wykazują znaczne różnice i w rzeczywistości stanowią odrębne jednostki chorobowe.

Komórki tuczne powstają w szpiku kostnym, skąd następnie migrują do różnych tkanek, m.in. do skóry i tkanki podskórnej. Charakterystyczne dla tych komórek są ziarnistości zawierające histaminę, heparynę i enzymy proteolityczne, które barwią się metachromatycznie błękitem toluidyny.

Lokalizacja i częstość występowania

U kotów guz komórek tucznych jest drugim co do częstości występowania nowotworem skóry, po raku podstawnokomórkowym (2, 11). Częstość występowania mastocytomy jest różna, ale ogółem stanowi 2-15% wszystkich nowotworów u kotów i zwykle diagnozuje się ją średnio w wieku dziewięciu lat (14).

Mastocytomy skórne zwykle występują pojedynczo, a guzy mnogie stanowią 11-14% wszystkich przypadków. Oprócz najpowszechniejszej postaci skórnej mastocytoma obejmuje również formy trzewne, które, mimo że występują rzadziej, są bardziej agresywne.

[...]
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Mogą zainteresować Cię również


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Wizytówka firmy


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Sklep


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