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Wpływ NLPZ na śluzówkę przewodu pokarmowego
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Streszczenie
Niesteroidowe leki przeciwzapalne (NLPZ) są najczęściej stosowanymi lekami na świecie; przyjmuje je 15% społeczeństwa, a około 5% wszystkich recept wystawianych jest na leki z tej grupy. NLPZ należą do najczęściej stosowanych preparatów w leczeniu ostrego i przewlekłego bólu w układzie ruchu zarówno u ludzi, jak i u psów. Dotychczas większość badań, dotyczących skutków ubocznych towarzyszących NLPZ u psów, ograniczała się do przedniej części przewodu pokarmowego, dzięki czemu powstało nie do końca trafne przeświadczenie, że do najcięższych uszkodzeń (nawet śmiertelnych) dochodzi w okolicach żołądka i dwunastnicy.
Słowa kluczowe
NLPZ, koksyby, okrężnica, endoskopia, skutki uboczne, psy
Abstract
Non-steroidal anti-inflammatory drugs (NSAIDs) are the most widely used drugs in the world, with 15% of the population using these medications, and about 5% of all prescriptions issued for drugs belonging to this group. NSAIDs are among the most commonly used preparations for the treatment of acute and chronic pain in the locomotor system in both humans and dogs. So far most studies on the associated side-effects of NSAIDs in dogs were confined to the upper part of the gastrointestinal tract, which often led to an improper conclusion that the greatest, even fatal, damages occur in the stomach and the duodenum.
Keywords
NSAIDs, coxibs, colon, [...]
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115
ALGORYTMY
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