Notice: Undefined index: test.vetkompleksowo.pl in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/plugins/custom-code/classes/s2k_post.php on line 124
Notice: Trying to access array offset on value of type null in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/plugins/custom-code/classes/s2k_post.php on line 124
Notice: Undefined index: test.vetkompleksowo.pl in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/plugins/custom-code/classes/s2k_post.php on line 128
Notice: Trying to access array offset on value of type null in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/plugins/custom-code/classes/s2k_post.php on line 128
Notice: Undefined index: test.vetkompleksowo.pl in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/plugins/custom-code/classes/s2k_post.php on line 132
Notice: Trying to access array offset on value of type null in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/plugins/custom-code/classes/s2k_post.php on line 132
Notice: Undefined index: test.vetkompleksowo.pl in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/plugins/custom-code/classes/s2k_post.php on line 136
Notice: Trying to access array offset on value of type null in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/plugins/custom-code/classes/s2k_post.php on line 136
Notice: Trying to get property 'id' of non-object in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/themes/weterynaria/inc/extras.php on line 663
Notice: Trying to get property 'id' of non-object in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/themes/weterynaria/inc/extras.php on line 678
Gabapentyna i pregabalina w leczeniu padaczki i bólu przewlekłego u zwierząt
Notice: Undefined index: test.vetkompleksowo.pl in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/plugins/custom-code/classes/s2k_post.php on line 124
Notice: Trying to access array offset on value of type null in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/plugins/custom-code/classes/s2k_post.php on line 124
Notice: Undefined index: test.vetkompleksowo.pl in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/plugins/custom-code/classes/s2k_post.php on line 128
Notice: Trying to access array offset on value of type null in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/plugins/custom-code/classes/s2k_post.php on line 128
Notice: Undefined index: test.vetkompleksowo.pl in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/plugins/custom-code/classes/s2k_post.php on line 132
Notice: Trying to access array offset on value of type null in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/plugins/custom-code/classes/s2k_post.php on line 132
Notice: Undefined index: test.vetkompleksowo.pl in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/plugins/custom-code/classes/s2k_post.php on line 136
Notice: Trying to access array offset on value of type null in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/plugins/custom-code/classes/s2k_post.php on line 136
Streszczenie
Gabapentyna i pregabalina to leki strukturalnie podobne do kwasu γ-aminomasłowego (GABA). Wiążą się z podjednostką alfa2-delta potencjałozależnych kanałów wapniowych w neuronach i poprzez obniżanie przepływu jonów wapnia hamują uwalnianie neuroprzekaźników pobudzających (np. noradrenaliny, substancji P). Wynika z tego ich działanie przeciwpadaczkowe i przeciwbólowe. U zwierząt mogą być wykorzystane jako leki wspomagające w leczeniu padaczki lub bólu przewlekłego (zwłaszcza neuropatycznego), w sytuacji gdy dotychczasowa terapia okazała się nieskuteczna.
Słowa kluczowe
gabapentyna, pregabalina, leki przeciwpadaczkowe, leki przeciwbólowe
Abstract
Gabapentin and pregabalin are structural analogues of γ-aminobutyric acid (GABA). They bind to alpha2-delta subunit of the voltage-gated calcium channels and by reducing calcium influx, they inhibit the release of excitatory neurotransmitters (e.g. norepinephrine, substance P). Gabapentin and pregabalin show antiepileptic and analgesic activity. In animals, gabapentin and pregabalin can be used as adjunctive therapy for refractory seizures or chronic pain, especially neuropathic pain, if conventional therapy is not effective.
Keywords
gabapentin, pregabalin, antiepileptic drugs, analgesic drugs
Ten materiał dostępny jest tylko dla użytkowników
którzy są subskrybentami naszego portalu.
którzy są subskrybentami naszego portalu.
Wybierz pakiet subskrypcji dla siebie
i ciesz się dostępem do bazy merytorycznej wiedzy!
i ciesz się dostępem do bazy merytorycznej wiedzy!
Masz aktywną subskrypcję?
Nie masz jeszcze konta w serwisie? Dołącz do nas
Notice: Trying to get property 'id' of non-object in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/themes/weterynaria/inc/extras.php on line 663
Notice: Trying to get property 'id' of non-object in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/themes/weterynaria/inc/extras.php on line 678
Notice: Trying to get property 'id' of non-object in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/themes/weterynaria/inc/extras.php on line 663
Notice: Trying to get property 'id' of non-object in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/themes/weterynaria/inc/extras.php on line 678
Notice: Trying to get property 'id' of non-object in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/themes/weterynaria/inc/extras.php on line 663
Notice: Trying to get property 'id' of non-object in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/themes/weterynaria/inc/extras.php on line 678
Notice: Trying to get property 'id' of non-object in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/themes/weterynaria/inc/extras.php on line 663
Notice: Trying to get property 'id' of non-object in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/themes/weterynaria/inc/extras.php on line 678
Notice: Trying to get property 'id' of non-object in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/themes/weterynaria/inc/extras.php on line 663
Notice: Trying to get property 'id' of non-object in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/themes/weterynaria/inc/extras.php on line 678
Zapisz się do bezpłatnego newslettera!
Bądź na bieżąco z nowościami z branży weterynaryjnej.
Notice: Trying to get property 'id' of non-object in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/themes/weterynaria/inc/extras.php on line 663
Notice: Trying to get property 'id' of non-object in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/themes/weterynaria/inc/extras.php on line 678
Mogą zainteresować Cię również
Notice: Trying to get property 'id' of non-object in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/themes/weterynaria/inc/extras.php on line 663
Notice: Trying to get property 'id' of non-object in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/themes/weterynaria/inc/extras.php on line 678
Notice: Trying to get property 'id' of non-object in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/themes/weterynaria/inc/extras.php on line 663
Notice: Trying to get property 'id' of non-object in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/themes/weterynaria/inc/extras.php on line 678
Notice: Trying to get property 'id' of non-object in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/themes/weterynaria/inc/extras.php on line 663
Notice: Trying to get property 'id' of non-object in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/themes/weterynaria/inc/extras.php on line 678
115
ALGORYTMY
POSTĘPOWANIA
w weterynarii
POSTĘPOWANIA
w weterynarii
Notice: Trying to get property 'id' of non-object in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/themes/weterynaria/inc/extras.php on line 663
Notice: Trying to get property 'id' of non-object in /home/users/elamed/public_html/portal_wiedzy_test/wp-content/themes/weterynaria/inc/extras.php on line 678
