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Właściwości interferonów oraz ich przydatność w praktyce klinicznej
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Streszczenie
Interferony są białkami należącymi do grupy cytokinin. Mają wpływ na układ odpornościowy oraz wykazują działanie przeciwnowotworowe. Podczas infekcji wirusowych zapewniają przekazywanie sygnału do układu odpornościowego oraz pobudzają prezentację antygenu komórkom T. Zwiększają odporność gospodarza na zakażenia wirusowe. Aktywują również makrofagi, komórki B, limfocyty T oraz pobudzają apoptozę. Uczestniczą w różnych interakcjach immunologicznych jako induktory, regulatory i efektory odporności zarówno wrodzonej, jak i odporności nabytej podczas infekcji wirusowych.
Słowa kluczowe
interferony, choroba, leczenie
Summary
Interferons are small proteins belonging to the cytokinin group. They have effect on immune system and inhibit the tumour growth. During viral infections they provide signal transmission to the immune system and stimulate antigen presentation to T cells. Interferons increase the host’s resistance to viral infections. They also activate the macrophages, B cells and alter the T cells and promote apoptosis. They are involved in various immune interactions as inducers, regulators and effectors of both innate immunity and acquired immunity during the viral infections.
Keywords
interferons, diseases, treatment
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POSTĘPOWANIA
w weterynarii
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