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Zaburzenia układu neuroendokrynnego u psów i kotów
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Streszczenie
Układ neuroendokrynny stanowi zbiór wyspecjalizowanych komórek rozsianych w wielu narządach wewnętrznych. Komórki neuroendokrynne są zlokalizowane w obrębie gruczołów endokrynnych – tarczycy (komórki C), rdzenia nadnerczy, wysp Langerhansa trzustki, a także w przewodach pokarmowym, oddechowym i moczopłciowym. Wykrywanie i leczenie nowotworów rozsianego układu neuroendokrynnego (NET) jest trudne, kosztowne i wymagające współpracy lekarzy wielu specjalności. Najczęstszym guzem neuroendokrynnym u zwierząt domowych jest insulinoma.
Słowa kluczowe
komórki neuroendokrynne, APUD, guzy neuroendokrynne
Abstract
The neuroendocrine system consists of diffuse cells in many internal organs. Neuroendocrine cells are localized in the endocrine organs: in the thyroid gland (C cells), adrenal medulla, Langerhans islets of pancreas, as well as in the gastrointestinal (GI tract) and the respiratory and urogenital tracts. The diagnosis and medical treatment of diffuse neuroendocrine cells tumors (NET) are difficult, expensive, and require cooperation of many specialists. The most common pancreatic islet tumor in animals which affects the insulin-secreting beta cells is called insulinoma.
Keywords
neuroendocrine cells, APUD, neuroendocrine tumors
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